Malaria kills more than 1 million people a year, mostly children in sub-Saharan Africa. Antimalarial drug resistance is one of the greatest challenges facing malaria control today. Ronald is a Domain-Specific Language to model the fundamental forces driving antimalarial drug resistance including drug pharmacokinetics and pharmacodynamics, drug regimens and parasite genotypes. Example of applications of this language include the study of the consequences of counterfeit or lower quality drugs, the impact of drug half life on the emerging and spread of resistance and the benefits and drawbacks of combination therapies, among others.

The current version of Ronald is still not usable (but feel free to download the existing code from the "Source" folder above). But we offer a prototype usable version made in Scala available on the main web site