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RNAO Expectations
Updated May 29, 2009 by michel.d...@gmail.com

Introduction

Ontology evokes a myriad of responses - from eye-rolling to fanatic enthusiasm. The goal of this page is to flesh out what people expect from an RNA ontology, so that we can better understand general and thought provoking requirements while identifying what an ontology can capture today, what still requires research and development in terms of knowledge representation languages and systems, and what is better handled at the application level.

Details

Vocabulary for:

  • Structure: from nucleic acid to atoms - their mereological and positional descriptions
  • Sequence: a simplification for string-based bioinformatic analyses
  • Interactions: base pairing, base stacking
  • ...

Rich descriptions about:

  • The bases in a trans Hoogsteen-Hoogteen base pair will be in parallel strands if they base orientations are anti.

  • ..

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