Could you please provide a script demonstrating the issue?  Specify also python 
version.

Is your PyScripter 2.4 version that has no problems 32 or 64 bit?  Is the 
problem by any chance related to Issue 617?

I can confirm this for Pyscripter 2.5 32 bit on Win7 64 bit & python 2.6 and 
also with Win7 32 bit & python 2.7.2. The Wxpython hello world program only 
shows the window if using the internal engine or the Tk one:

import wx
app = wx.App(False) 
frame = wx.Frame(None, wx.ID_ANY, "Hello World") 
frame.Show(True)    
app.MainLoop()

Pyscripter 2.4.3 32 bit works as expected.

My python version is 2.7 32 bit.

Not sure which pyscripter bittage I have installed. The about menu doesnt say, 
but its in program files (x86), though I believe that does not necessarily 
prove anything? My policy is to download the bittage corresponding to my OS.

I dont see any resemblance to issue 617

I will try to release an update to sort this.

2.5.2 fixes this.

It does indeed - thanks very much for a great IDE!

Works for me; thank you so much for the rapid fix, and the best python editor 
in general! :)