Note: This is more of a task/enhancement, but for some reason I could only enter it as 
a 'defect'.

How do you imagine such an integration? What would the API/end user code look like? 
I've yet to do any serious work with ZF, but making Minify easier to work into 
existing frameworks is a goal I'm behind.

At the very least we could host some code in the repo/guide on the wiki.

I've done some integration with Zend Framework on projects I work on, and so far its
consisted of the following pieces:

-config file that is an array of js or css files
-section in the Initializer that uses Zend_Registry to register the array of js/css
to be used by other classes (view helper)
-view helper use Minify_Build and config array in Zend_Registry to render the script
include, or include the scripts un-minified if a disabled flag is set (useful for
development)
-last piece is a js.php or css.php file in the public that gets the same js/css
config array, and actually outputs the minified data using Minify::serve();

There may be a better way, but so far that's what I've come up with.  I'd be glad to
help out with sharing the View Helper, and other pieces of code as a tutorial of sorts.